Amy Schumer has spoken about her health. The comedian revealed in a live event podcast On May 17’s Not Thin, But Not Fat with host Amanda Hirsch, she said she recently had a “bad colonoscopy”, which left her feeling less than her best.
When Hirsch pointed out her noticeable weight loss and asked if her happiness had anything to do with “getting really hot,” Schumer kept it real. “My colonoscopy was actually kind of a failure, so I’m not feeling too horny,” she said. per hola. He did not go into further detail about what exactly went wrong during the procedure. “This is one more thing you won’t have to worry about for 15 years,” he said.
Despite the health setback, Schumer also said she is in good shape overall. “I feel happier than ever,” she said at the event. Entertainment Weekly.
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What health condition did Amy Schumer deal with during her weight loss journey?
Schumer’s health journey took a turn for the worse when people online began noticing her swollen face in early 2024. Rather than being hurt by the comments, he said they actually helped him realize that something was wrong. “In addition to the fear about my health, I also had to be in front of the camera with the sound of the Internet. But thank God for that. Because that’s how I realized that something was wrong. The Internet is undefeated, as they say,” he told journalist Jessica Yellin in her News Not Noise newsletter, per Hola.
She was diagnosed with Cushing’s syndrome, a hormonal disorder caused by elevated cortisol levels, triggered by the steroid injections she received. “I was taking these steroid injections, and it gave me a disease called Cushing’s syndrome, which I wouldn’t have known about if the Internet hadn’t come to me so hard,” she said on the Call Her Daddy podcast in 2025, according to Entertainment Weekly.
Once the condition was cleared, Schumer lost 50 pounds but made it clear that it was never about looks. “I lost not 30 pounds, but 50 pounds. Not to look hot, that feels fun and temporary. I did it to survive,” she wrote on Instagram last December.
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Amy Schumer talks about plastic surgery and Monjaro
Schumer has been open about every part of her health journey. She confirmed that she takes Monjaro for weight management, although she no longer uses Botox or fillers. According to Hola, she said, “I’m sorry for any feeling you may have that I’ve lost weight. I’ve had plastic surgery over the years and I use Monjaro.”
“Sorry to disappoint anyone. I’m pain free.”
In a November Instagram update, she shared good news about her overall health. According to Hola, she wrote, “I’ve been working to be pain-free and I’m finally doing it. I no longer have Cushing’s syndrome, so my face is back to normal. I’m grateful to be strong and healthy, especially for my son.”
On December 12, she announced her separation from ex-husband Chris Fischer on Instagram. “Chris and I have made the difficult decision to end our marriage after 7 years. We love each other very much and will continue to focus on raising our son. We would appreciate people respecting our privacy at this time,” she wrote.